When considering the role of the key immune molecule interleukin (IL)-17, the phrase "too much of a good thing" springs to mind. Because unlike some of its more sedate cytokine cousins which studiously direct the immune response ...
Jun 3, 2019
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Children (and adults) with hemophilia are slow to form blood clots, so are at constant risk for uncontrolled bleeding. Even when the skin isn't broken, a fall or a simple toe stub can become a serious medical issue: internal ...
Mar 10, 2020
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Working with a group of national and international researchers, scientists from the Florida campus of The Scripps Research Institute have developed a new genetic model of premature aging disorders that could shed light on ...
Apr 29, 2011
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Toronto scientists have discovered that the largest group of human proteins, which work as genome gatekeepers to control gene activity, are even more diverse in their roles than previously thought. The finding expands our ...
Nov 29, 2016
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Researchers at the Centre for Genomic Regulation (CRG) have found that the Snhg11 gene is critical for the function and formation of neurons in the hippocampus. Experiments with mice and human tissues revealed that the gene ...
Feb 26, 2024
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Huntington's disease is the most common neurodegenerative disorder controlled by a single gene and is characterized by motor and cognitive deficits and psychiatric symptoms. Currently, no treatments can stop or reverse the ...
Oct 13, 2023
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Researchers at Mount Sinai School of Medicine, the University of Manchester, and the MD Anderson Cancer Center have found a new role for an oncogenic signaling pathway in embryonic stem cell (ESC) self-renewal and in reprogramming ...
Aug 3, 2012
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Researchers from Harvard, NC State and five other universities have found a specific genetic on-off switch associated with obesity in both mice and humans, raising the long-term possibility of developing new treatments for ...
Jul 19, 2013
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Advancing the understanding of synovial sarcoma, a highly aggressive and rare cancer of young people, scientists at Dana-Farber Cancer Institute have discovered how an abnormal protein misdirects and disrupts the control ...
Aug 3, 2020
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A genetic modification in a "clock gene" that influences circadian rhythm produced significant changes in the length and magnitude of cycles, providing insight into the complex system and giving scientists a new tool to further ...
Feb 13, 2018
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