Autosomal dominant polycystic kidney disease (ADPKD) is the most common potentially lethal genetic disease—about a half million people in the United States alone suffer from the condition. There is no cure, but new research ...
Apr 3, 2023
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Mutations in the BRCA1 and BRCA2 genes pose a serious risk for breast and ovarian cancer because they endanger the genomic stability of a cell by interfering with homologous recombination repair (HR), a key mechanism for ...
Dec 3, 2018
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Scientists at Scripps Research have developed a new tool to monitor brain plasticity—the way our brains remodel and physically adapt as we learn and experience things, from watching a movie to learning a new song or language. ...
Oct 19, 2022
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University of Louisville researchers have replicated the inflammatory gene changes of a human kidney as it progresses from mild to severe diabetic nephropathy, using a mouse model developed by a UofL researcher, according ...
May 23, 2011
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To find new treatment approaches for childhood cancer, scientists at St. Jude Children's Research Hospital are digging deep into disease biology to target a process long considered "undruggable." The approach revealed a new ...
Jul 13, 2022
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Leading muscular dystrophy researcher Dean Burkin, of the University of Nevada School of Medicine summarizes the impact of a new protein therapeutic, MG53, for the treatment of Duchenne muscular dystrophy in an article published ...
Jun 22, 2012
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Researchers at the University of Virginia School of Medicine have discovered a new potential contributor to age-related hearing loss, a finding that could eventually help doctors identify people at risk.
Mar 12, 2019
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Researchers at Lund University in Sweden have discovered a direct link between the protein aggregation in nerve cells that is typical for neurodegenerative diseases, and the regulation of gene expression in Huntington's disease. ...
Aug 21, 2018
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A new Brown University computer analysis that predicts the effect of genetic mutations on how the body splices mRNA indicates as many as a third of disease-related mutations may be linked to splicing problems -- more than ...
Jun 13, 2011
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When considering the role of the key immune molecule interleukin (IL)-17, the phrase "too much of a good thing" springs to mind. Because unlike some of its more sedate cytokine cousins which studiously direct the immune response ...
Jun 3, 2019
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