New HHMI research reveals how three proteins help brain cells synchronize the release of chemical signals. A similar interaction may play a role in how cells secrete insulin and airway mucus, too.
Sep 13, 2017
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EPFL spin-off Cellestia Biotech has just been given the regulatory go-ahead to start clinical testing a molecule it has developed to treat cancers involving mutations of the Notch gene. The molecule is a ray of hope for the ...
Sep 1, 2017
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It turns out that bile is a lot more dynamic than you might think. One of the biggest factors affecting bile, which is very important to our ability to absorb nutrients, is our diet. But another is the make-up of the community ...
Aug 29, 2017
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Northwestern Medicine scientists have identified a novel molecular mechanism that regulates scar formation in the heart, a common manifestation of aging and nearly every form of heart disease. The discovery was published ...
Jul 13, 2017
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An essential protein that regulates our heart beat turns out to be important for cancer cells as well. The discovery might open novel treatment strategies for fighting metastasis. Publication in Science Signaling on April ...
Apr 5, 2017
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Learning and memory are crucial aspects of everyday life. When we learn, our neurons use chemical and molecular signals to change their shapes and strengthen connections between neurons, a process known as synaptic plasticity. ...
Mar 9, 2017
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(Medical Xpress)—Few classes of drugs have galvanized the pharmaceutical industry in recent times like the cannabinoids. This class of molecules includes not only the natural forms, but also a vast new treasury of powerful ...
Research has shown that the growth of cancerous tumours is affected by transforming growth factor (TGFβ) in the body's cells; TGFβ both suppresses and stimulates tumour development. But it has not been understood how this ...
Aug 23, 2016
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Research by Dr. Shernaz Bamji, from the University of British Columbia, uncovers the mechanism of action of an enzyme called DHHC9 in the normal development and function of neural networks in the brain. Mutations in DHHC9 ...
May 30, 2016
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While research has identified hundreds of genes required for normal memory formation, genes that suppress memory are of special interest because they offer insights into how the brain prioritizes and manages all of the information, ...
Apr 14, 2016
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