When Joanina Gicobi began her Ph.D. degree five years ago at Mayo Clinic Graduate School of Biomedical Sciences, she was interested in thinking creatively about ways to improve cancer treatment. In particular, she was curious ...
Dec 4, 2023
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Lidocaine—often used as a numbing agent for outpatient medical procedures—activates certain bitter taste receptors through two unique mechanisms that result in cancer cell death, according to researchers from the Perelman ...
Nov 22, 2023
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Researchers from the Center for Translational Immunology at University Medical Center Utrecht (the Netherlands) have identified that a transient inflammatory pain causes mitochondrial and redox changes in sensory neurons ...
Nov 8, 2023
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A research team led by scientists from City University of Hong Kong (CityU) has achieved a significant breakthrough by inventing a new class of near-infrared-activated photo-oxidants that can effectively kill cancer cells ...
Sep 20, 2023
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Yale researchers have found that liver fibrosis—scarring of the liver tissue that occurs in many chronic liver diseases—is associated with reduce cognitive ability and, in certain regions of the brain, reduced brain volume. ...
Jun 26, 2023
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The vast majority of diseases and disorders afflicting humans, ranging from arthritis to Zika fever, involve some level of inflammation. While inflammation is most familiar to us as pain, redness, and swelling, a slew of ...
Jun 22, 2023
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Oxidative stress—characterized by elevated levels of unstable molecules called reactive oxygen species—is associated with neurodegeneration and cardiovascular disease. However, until recently it has not been possible ...
Jun 14, 2023
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In a world first, Newcastle researchers have discovered the mechanisms acute myeloid leukemia (AML) cells use to produce "free radicals"—the byproduct of a cell process that aggressively fuels the growth of cancer cells ...
Mar 29, 2023
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In a new study, researchers found that the PFAS chemical GenX suppresses the neutrophil respiratory burst—the method white blood cells known as neutrophils use to kill invading pathogens. The study is an important first ...
Feb 15, 2023
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Scientists have discovered there is a "Goldilocks" effect in identifying the size of a "vaccine adjuvant" that can trigger strong immune responses and, as an example, have shown that a safe, biodegradable adjuvant can boost ...
Jan 20, 2023
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