Researchers have found cell receptors abnormally overexpressed in post-mortem brains of those with Parkinson's and Alzheimer's diseases, and that they can be inhibited in animal models to clear toxic protein buildup, reduce ...
Jul 16, 2017
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For the first time, researchers have uncovered the significance of the molecular assembly processes—called biogenesis—of AMPA-type glutamate receptors for proper operation of the human brain. AMPA receptors, the most ...
Jul 7, 2017
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Research from King's College in London, UK, and Lund University in Sweden could explain why diabetes drugs which have worked in animal experiments are not equally successful in humans. The researchers discovered differences ...
Jul 3, 2017
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Researchers at The University of Texas Medical Branch at Galveston have shed light on how the developing brain ensures that connections between brain cells reach their intended destination but that they are also maintained ...
Jun 21, 2017
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Researchers in Japan have identified a receptor protein on the surface of heart cells that promotes chronic heart failure. The study, "Corticotropin releasing hormone receptor 2 exacerbates chronic cardiac dysfunction," which ...
May 26, 2017
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Epilepsy and intellectual disability, which usually have their onset during childhood, are in some cases linked to mutations in the gene KIAA1202, which contains the information to produce the protein Shrm4. An international ...
May 15, 2017
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Revelations about a protein expressed in fetal cells could provide novel insights into its function and future immunosuppressive therapies.
May 10, 2017
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Scientists at Columbia University have obtained the first detailed images of interactions between the AMPA receptor and molecules that regulate chemical signaling in the brain. Their findings may help understand the processes ...
May 3, 2017
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Research at the University of Illinois at Urbana-Champaign has provided the first evidence that viruses and hosts share highly similar regulatory sequences in their promoters—the initiation sequences of human genes that ...
May 2, 2017
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Researchers at Houston Methodist demonstrated that a surface protein called OX40, responsible for keeping one type of immune system cell alive, can trigger the death of liver immune cells, in turn starting a chain reaction ...
Apr 24, 2017
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