Medical research

Discovery suggests route to safer pain medications

Strategies to treat pain without triggering dangerous side effects such as euphoria and addiction have proven elusive. For decades, scientists have attempted to develop drugs that selectively activate one type of opioid receptor ...

Neuroscience

Astrocyte dysfunction found to cause cognitive decline

People with dementia have protein build-up in astrocytes that may trigger abnormal antiviral activity and memory loss, according to a preclinical study by a team of Weill Cornell Medicine investigators.

Medical research

How opioid drugs get into our cells

The human body naturally produces opioid-like substances, such as endorphins, that block the perception of pain and increase the feeling of well-being. Similarly, opioid drugs, including morphine or fentanyl, are widely used ...

Medical research

Marijuana-derived compounds could reverse opioid overdoses

There's been a recent push in the U.S. to make naloxone—a fast-acting opioid antidote—available without a prescription. This medication has saved lives, but it's less effective against powerful synthetic opioids, such ...

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