A new computational method developed by scientists from the University of Chicago improves the detection of genes that are likely to be causal for complex diseases and biological traits. The method, PrediXcan, estimates gene ...
Aug 10, 2015
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Recent investigations have shown that our genome and those of other mammals is partitioned into large functional units called topologically associated domains, or TADs for short. TADs are very long DNA sections containing ...
May 13, 2015
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The early stages of embryonic development shape our cells and tissues for life. It is during this time that our newly formed cells are transformed into heart, skin, nerve or other cell types. Scientists are finding that this ...
Feb 23, 2015
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A team of researchers from USC and NYU has developed and patented a small molecule that interferes with cancer progression with minimal side effects.
May 13, 2014
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(Medical Xpress)—Cystic fibrosis is caused by a mutation in the gene that encodes a particular protein, known as the cystic fibrosis transmembrane conductance regulator (or CFTR). Although this discovery was made 25 years ...
Jul 9, 2013
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There's not much difference between what makes a man and what makes his beer - at least at the molecular level - according to a new study led by Professor John Schwabe at the University of Leicester.
Jul 1, 2013
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New research suggests that a compound abundant in the Mediterranean diet takes away cancer cells' "superpower" to escape death. By altering a very specific step in gene regulation, this compound essentially re-educates cancer ...
May 20, 2013
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(Medical Xpress)—Researchers at the Wellcome Trust Sanger Institute and University of Cambridge have unpicked genetic variants that affect the formation of blood cells. They found that around a third of the variants play ...
Apr 17, 2013
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Through a collaborative genome-wide study on individuals, researchers have discovered 14 new genetic variations that are associated with heart rate. Since heart rate is a marker of cardiovascular health, these findings could ...
Apr 14, 2013
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In a surprising finding that helps explain fundamental behaviors of normal and diseased cells, Whitehead Institute scientists have discovered a set of powerful gene regulators dubbed "super-enhancers" that control cell state ...
Apr 11, 2013
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