Healthy cells and cells with type 2 diabetes use completely different pathways to manage blood sugar levels, according to results from a study in mice. Researchers used a trans-omic approach, combining data from genes (transcriptomics) ...
Dec 1, 2020
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A flurry of coordinated activity in a brain-spanning network of neurons may sound like the formation of a brilliant new idea, but it is actually the description of a seizure. Understanding why and how this synchronization ...
Sep 13, 2016
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Gradual disruption of various processes in our cells results in ageing. Now scientists at the Max Planck Institute for Biology of Ageing in Cologne have discovered a network of regulatory molecules that converge to prevent ...
Apr 5, 2016
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Despite decades of research on the bacterium that causes tuberculosis (TB), scientists have not had a comprehensive understanding of how the bacterium is wired to adapt to changing conditions in the host. Now, researchers ...
Jul 3, 2013
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University of North Carolina researchers have discovered that disrupting a gene that acts as a regulatory switch to turn on other genes can keep blood vessels from forming and developing properly.
Apr 29, 2013
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(Medical Xpress)—Researchers at the University of Michigan have determined how the hormone leptin, an important regulator of metabolism and body weight, interacts with a key receptor in the brain.
Oct 11, 2012
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The massive Encyclopedia of DNA Elements (ENCODE) unveiled Sept. 5 reveals a human genome vastly more rich and complex than envisioned even a decade ago. In a key supporting paper published in the journal Nature, the lab ...
Sep 5, 2012
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New York University and University of Iowa biologists have identified a key mechanism controlling early embryonic development that is critical in determining how structures such as appendages -- arms and legs in humans -- ...
Oct 21, 2011
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When healthy people are faced with threatening situations, they react with a suitable behavioural response and do not descend into a state of either panic or indifference, as is the case, for example, with patients who suffer ...
Sep 6, 2011
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Triple-negative breast cancer (TNBC) is an aggressive type of breast cancer with a high fatality rate. Currently, chemotherapy is the major treatment option, but the clinical result is unsatisfactory. A research team led ...
Apr 15, 2021
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