Medical research

Aberrant mTOR signaling impairs whole body physiology

The protein mTOR is a central controller of growth and metabolism. Deregulation of mTOR signaling increases the risk of developing metabolic diseases such as diabetes, obesity and cancer. In the current issue of the journal ...

Oncology & Cancer

Exercising restraint to stall tumor growth

Many proteins undergo an assembly line-style process of glycosylation as they travel from a cellular structure called the endoplasmic reticulum (ER) to the Golgi apparatus and on through its various compartments, after which ...

Medical research

When the isolated lung runs out of air

A lung transplant is the only treatment option for patients faced with imminent pulmonary failure. But suitable donor organs are highly susceptible to damage in transit. A team of researchers based at LMU's Walther Straub ...

Immunology

How regulatory T cells halt aberrant, self-reactive T cells

New research findings show in detail how self-reactive T cells—white blood cells that mistakenly attack healthy instead of infected cells, thereby causing an autoimmune or an inflammatory response—are held in check by ...

Medical research

Iron regulators join war on pathogens

Proteins responsible for controlling levels of iron in the body also play an important role in combatting infection, according to a study published today in Cell Host & Microbe.

Medical research

Putting a 'HEX' on muscle regeneration

A complex genetic regulatory network mediates the regeneration of adult skeletal muscles. In this issue of the Journal of Clinical Investigation, researchers at the State University of New York Downstate Medical Center in ...

page 6 from 9