T cells—immune cells that patrol our bodies in search of trouble—have become a central focus for UC San Francisco scientists working on living cell therapies, an approach that views cells themselves as a form of medicine.
Jun 18, 2021
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Therapies based on natural immune system cells hold great potential for treating autoimmune diseases and reducing the number of graft rejections. However, harvesting enough cells from healthy donors in their pure, uncontaminated ...
May 6, 2016
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A new Finnish study from the University of Turku shows that a 30-minute exercise session can increase the proportion of tumor-killing white blood cells in the bloodstream of breast cancer patients.
Jul 3, 2024
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Graft-versus-host disease (GVHD) is a serious risk in many kinds of cell transplants, including for stem cell transplants carried out when stem cells are partially depleted of conventional T cells, which play an important ...
Oct 31, 2011
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Researchers at St. Jude Children's Research Hospital have discovered the mechanism by which immune cells called regulatory T cells keep themselves intact and functional during their demanding task of holding the immune system ...
Jan 25, 2016
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(Medical Xpress)—More than a million people die each year of malaria caused by different strains of the Plasmodium parasite transmitted by the Anopheles mosquito. The medical world has yet to find an effective vaccine against ...
Dec 3, 2012
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Dogs are proving to be a far better scientific model for study of prostate cancer than mice, the typical animal used in the lab for this type of research. In the first use of canines in an advanced prostate cancer study, ...
Feb 7, 2022
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Immune checkpoint inhibitors are a type of therapy that uses the immune system to fight cancer. They have been hailed as game changing, garnering a Nobel Prize last year and quickly becoming the standard of care for many ...
Sep 5, 2019
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Professor Yi Sun's team at the Zhejiang University report a functional compensatory effect between the Ube2m-Rbx1 and Ube2f-Sag axes of the neddylation–Cullin-RING ligases (CRLs) system in Treg cells, using conditional ...
Dec 22, 2023
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When T cells, the immune system's chief cancer-killing agents, are working overtime to battle a tumor, they can enter a state of exhaustion where they no longer function properly. In a new Nature Immunology study, University ...
Dec 21, 2022
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