Neuroscience
Allopurinol may cut risk for neurodegenerative diseases
Xanthine dehydrogenase/oxidase blockers may reduce the risk for neurodegenerative diseases, according to a study published online May 17 in PLOS ONE.
May 19, 2023
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Page 6 - News tagged with replication
Medical research
DNA replication discovery opens paths to understanding and treating cancer, aging and degenerative disease
An international collaboration steered by David Cortez, Richard N. Armstrong, Ph.D. Chair for Innovation in Biochemistry, explored how cells tolerate DNA damage and genome instability—and they arrived at conclusions that ...
May 3, 2023
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Oncology & Cancer
Two studies find role for alternative lengthening of telomeres in treatment-resistant tumors
Two recent papers from researchers in the Children's Hospital of Philadelphia (CHOP) Cancer Center have advanced the understanding of treatment-resistant pediatric tumors, both in assessing a novel treatment and in characterizing ...
Apr 27, 2023
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Diseases, Conditions, Syndromes
Study highlights the links between air quality and COVID-19 severity
A recently published article in Experimental Biology and Medicine addresses the mechanisms by which air pollution worsens COVID-19, highlighting the apparent protection offered by a dietary antioxidant, astaxanthin.
Apr 20, 2023
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Oncology & Cancer
Olaparib plus ceralasertib may benefit pediatric cancer patients with DNA-repair-deficient tumors
A combination of the PARP inhibitor olaparib (Lynparza) and the investigational ATR inhibitor ceralasertib showed clinical benefit in pediatric patients with solid tumors exhibiting DNA replication stress and/or DNA repair ...
Apr 18, 2023
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HIV & AIDS
A plant-based compound that inhibits reactivation of the HIV viral reservoir, giving the immune system a break
As of 2022, approximately 1.2 million people in the United States are living with HIV. Antiretroviral therapies have enabled many of these individuals to live productive, symptom-free lives, but a cure that permanently eliminates ...
Mar 28, 2023
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HIV & AIDS
New directions for HIV treatment
Northwestern Medicine scientists have identified a new compound which could inform future HIV cure strategies, according to research published in Science Advances.
Mar 22, 2023
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Medical research
New study finds co-infection with 'superbug' bacteria increases SARS-CoV-2 replication
Global data shows nearly 10 percent of severe COVID-19 cases involve a secondary bacterial co-infection—with Staphylococcus aureus, also known as staph A, being the most common organism responsible for co-existing infections ...
Mar 20, 2023
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Medications
Real-world studies confirm effectiveness of bulevirtide to treat chronic hepatitis D
In 2020, bulevirtide (BLV) was conditionally approved for treating chronic hepatitis delta (CHD), an inflammation of the liver caused by hepatitis D virus (HDV). Now real-world studies of patients treated outside of clinical ...
Mar 20, 2023
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Diseases, Conditions, Syndromes
Dengue treatment advances in animal trials
A new dengue treatment that could become the first to prevent and treat the virus has proven effective in initial trials in monkeys, according to new research.
Mar 16, 2023
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