The biguanides are a family of drugs with diverse clinical applications. Metformin, a widely used anti-hyperglycemic biguanide, suppresses mitochondrial respiration by inhibiting respiratory complex I. Phenformin, a related ...
Aug 11, 2016
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An international group of scientists from the U.S., Canada, Germany and Russia has revealed a naturally occurring organic compound that can suppress the pro-inflammatory activity of macrophages. The compound, itaconate, is ...
Jul 1, 2016
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Safety evaluation is a critical part of drug and cosmetic development. In recent years there is a growing understanding that animal experiments fail to predict the human response, necessitating the development of alternative ...
Aug 17, 2015
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Can the process of aging be delayed or even reversed? Research led by specially appointed Professor Jun-Ichi Hayashi from the University of Tsukuba in Japan has shown that, in human cell lines at least, it can. They also ...
May 26, 2015
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Meclizine, an over-the-counter drug used for decades to treat nausea and motion sickness, has the potential for new uses to treat certain infectious diseases and some forms of cancer, according to Dr. Vishal M. Gohil, Texas ...
Oct 30, 2013
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The premature baby's life is well monitored, but precarious.
Sep 13, 2013
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February 15, 2013 – Doctors currently struggle to determine whether a breast tumor is likely to shift into an aggressive, life-threatening mode—an issue with profound implications for treatment. Now a group from The Scripps ...
Feb 15, 2013
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A protein known to regulate how cells process glucose also appears to be a tumor suppressor, adding to the potential that therapies directed at cellular metabolism may help suppress tumor growth. In their report in the Dec. ...
Dec 6, 2012
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Flemish biologists lead by Joris Messens (VIB / Vrije Universiteit Brussel) have discovered that Mycobacterium tuberculosis – the bacterium that causes tuberculosis – has an ingenious defence mechanism against oxygen. ...
Nov 14, 2012
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(Medical Xpress)—Errors in the operating theatre can have tragic consequences. Researchers from ETH Zurich and the University Hospital Zurich demonstrate that the efficiency of anaesthesia teams depends greatly on their ...
Nov 1, 2012
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