Scientists who developed a technology for identifying and targeting unique protein receptor ZIP Codes on the cellular surface have found a way to penetrate the outer membrane and deliver engineered particles - called iPhage ...
Apr 17, 2012
0
0
A group of ribosomal protein genes connect animal models of depression to human patients with major depressive disorder. In order to research depression treatments, scientists use a mouse model, inducing a state with similarities ...
Oct 11, 2023
0
26
With around 90% of drugs failing to make it to market, the potential for improving efficiency within the drug development industry is clear. Drugs designed to combat cancers suffer similar rates of failure for many reasons. ...
Aug 23, 2023
0
4
Muscle wasting, or the loss of muscle tissue, is a common problem for people with cancer, but the precise mechanisms have long eluded doctors and scientists. Now, a new study led by Penn State researchers gives new clues ...
Feb 3, 2021
0
5
Hypoxia—where a tissue is deprived of an adequate supply of oxygen—is a feature inside solid cancer tumors that renders them highly invasive and resistant to treatment. Study of how cells adapt to this critical stressor, ...
Feb 3, 2021
0
13
The lungs and placentas of fetuses in the womb—as young as 11 weeks after conception—already show a bacterial microbiome signature, which suggests that bacteria may colonize the lungs well before birth. This first-time ...
Jan 17, 2020
0
12
Nearly 90 percent of all cancer patient deaths are due to metastasis. A study from Uppsala University shows that a process that allows the cells to metastasise is aided by the synthesis of new ribosomes, the cell components ...
May 8, 2019
0
0
Aging is a risk factor for the development of osteoarthritis (OA), a chronic disease characterized by degeneration of articular cartilage leading to pain and physical disability. Senescent mesenchymal stem cells (hMSCs) are ...
Mar 28, 2019
0
27
Ever since the 1960s, the researchers have wondered why some patients who suffer from illnesses resulting from inadequate cell division are much more susceptible to cancer, which is conversely characterized by excessive cell ...
Nov 29, 2018
0
5
Research from the University of Toronto has shown that in some neurodegenerative diseases, two hallmarks of cell aging – protein aggregation and a type of DNA instability – are linked. They were previously thought to ...
Nov 21, 2018
0
20
