Diseases, Conditions, Syndromes

Belimumab promising in combination therapy for refractory lupus

For patients with systemic lupus erythematosus (SLE) refractory to conventional treatment, belimumab after rituximab significantly reduces serum immunoglobulin (Ig)G anti-double stranded DNA (dsDNA) levels and the risk for ...

Medications

Rituximab, mycophenolate mofetil compared for pemphigus vulgaris

(HealthDay)—For patients with pemphigus vulgaris, rituximab is superior to mycophenolate mofetil for producing sustained complete remission at 52 weeks, according to a study published online May 19 in the New England Journal ...

Oncology & Cancer

Anti-cancer drug's mode of operation deciphered

Rituximab, an anti-cancer drug targeting the membrane protein CD20, was the first approved therapeutic antibody against B tumor cells. Immunologists at the University of Freiburg have now solved a mystery about how it works. ...

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