Medical research

Protein 'motif' crucial to telomerase activity

It is difficult to underestimate the importance of telomerase, an enzyme that is the hallmark of both aging and the uncontrolled cell division associated with cancer. In an effort to understand and control telomerase activity, ...

Medical research

New powerful tool measures metabolites in living cells

By engineering cells to express a modified RNA called "Spinach," researchers have imaged small-molecule metabolites in living cells and observed how their levels change over time. Metabolites are the products of individual ...

Parkinson's & Movement disorders

Parkinson's database gets massive dose of RNA

A team at the Keck School of Medicine of USC, in collaboration with The Michael J. Fox Foundation for Parkinson's Research (MJFF), has just added a crucial new element—RNA sequencing data—to its robust study of Parkinson's ...

Genetics

Conspicuous tRNA lookalikes riddle the human genome

Transfer RNAs (tRNAs) are ancient workhorse molecules and part of the cellular process that creates the proteins, critical building blocks of life that keep a cell running smoothly. A new discovery suggests that the number ...

Genetics

Overcoming a major barrier to developing liquid biopsies

The idea of testing blood or urine to find markers that help diagnose or treat disease holds great promise. But as technology has improved to allow researchers to examine tiny fragments of RNA, one major problem has led to ...

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