Medical research

Using artificial RNA editing to restore genetic code

Various genetic diseases caused by point mutations have no established therapeutic approaches. Prof. Tsukahara and colleagues (Japan Advanced Institute of Science and Technology) are studying a therapeutic method using artificial ...

Medical research

Allergic asthma transforms cells of the airway

New research at National Jewish Health shows that allergic asthma fundamentally transforms the human airway, reducing cells' ability to remove pollutants and fight infections. Allergic asthma, the most common form of the ...

Oncology & Cancer

New research uncovers how common genetic mutation drives cancer

A new, multicenter study led by Fred Hutchinson Cancer Research Center and Memorial Sloan Kettering Cancer Center determined how a single mutation in splicing factor 3b subunit 1 (SF3B1), the most frequently mutated splicing ...

Inflammatory disorders

Drug resistance signature discovered in Crohn's disease

By mapping out more than 100,000 immune cells in patients with Crohn's disease, Mount Sinai researchers have discovered a signature of cells that are involved in a type of the disease that does not respond to treatment, according ...

Genetics

Predicting how splicing errors impact disease risk

No one knows how many times in a day, or even an hour, the trillions of cells in our body need to make proteins. But we do know that it's going on all the time, on a massive scale. We also know that every time this happens, ...

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