Genetics

How mutations in a high risk gene affect motor neurons

Scientists at the flagship motor neuron disease research centre, based at the University of Sheffield, investigated how specialised nerve cells that control voluntary movements die – something which is key to understanding ...

Medical research

Scientists turn muscular dystrophy defect on and off in cells

For the first time, scientists from the Florida campus of The Scripps Research Institute (TSRI) have identified small molecules that allow for complete control over a genetic defect responsible for the most common adult onset ...

Genetics

Gene variants found to affect human lifespan

By broadly comparing the DNA of children to that of elderly people, gene researchers have identified gene variants that influence lifespan, either by raising disease risk or by providing protection from disease.

Medical research

Regulating single protein prompts fibroblasts to become neurons

Repression of a single protein in ordinary fibroblasts is sufficient to directly convert the cells – abundantly found in connective tissues – into functional neurons. The findings, which could have far-reaching implications ...

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