Diseases, Conditions, Syndromes

Study details microRNA's role as a double agent during Hep C infection

In the battle between a cell and a virus, either side may resort to subterfuge. Molecular messages, which control the cellular machinery both sides need, are vulnerable to interception or forgery. New research at Rockefeller ...

Oncology & Cancer

Lack of RNA 'editing' leads to melanoma growth and metastasis

The importance of RNA editing in melanoma has been demonstrated by scientists at The University of Texas MD Anderson Cancer Center. The study revealed that a lack of RNA editing, a process by which information inside RNA ...

Oncology & Cancer

A noncoding RNA promotes pediatric bone cancer

Ewing sarcoma is a cancer of bone or its surrounding soft tissue that primarily affects children and young adults. A hallmark of Ewing sarcoma is a translocation event that results in the fusion of an RNA binding protein, ...

Genetics

Cellular suicide switch discovered

A newly discovered early-warning system triggers cellular suicide when a critical RNA editing system breaks down.

Genetics

Understanding the effects of genes on human traits

Recent technological developments in genomics have revealed a large number of genetic influences on common complex diseases, such as diabetes, asthma, cancer or schizophrenia. However, discovering a genetic variant predisposing ...

Oncology & Cancer

RNA promotes metastasis in lung cancer

The vast majority – approximately 80 percent – of our DNA does not code for proteins, yet it gets transcribed into RNA. These RNA molecules are called non-coding and fulfill multiple tasks in the cell. Alongside a well-studied ...

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