Researchers from the Icahn School of Medicine at Mount Sinai have shed valuable light on the nuanced functions and intricate regulatory methods of RNA editing, a critical mechanism underlying brain development and disease.
Jun 28, 2024
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Researchers from Children's Hospital of Philadelphia (CHOP) revealed the mechanisms behind one particular molecule's involvement in regulating insulin sensitivity. The findings, which were translated from a preclinical animal ...
Jun 28, 2024
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A large team of medical researchers at the University of California, San Francisco, and CellSight Technologies has found that some patients who develop long COVID show signs of uncharacteristic immune cell activity in many ...
A study, titled "Single-cell transcriptomic Atlas of aging macaque ocular outflow tissues" appearing in Protein & Cell, delves into the age-related changes in the trabecular meshwork (TM) of macaques, which are vital for ...
Jul 11, 2024
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Addressing problems with diagnosing and treating breast cancer, scientists at EPFL have developed EMBER, a tool that integrates breast cancer transcriptomic data from multiple databases. EMBER can improve precision oncology ...
Jul 19, 2024
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Peter Mac researchers have taken the first step towards designing rapid personalized cancer treatments by 'cutting out' disease-causing RNA.
Jul 2, 2024
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A pair of recent studies led by Joseph Mazzulli, Ph.D., associate professor in The Ken & Ruth Davee Department of Neurology's Division of Movement Disorders, have uncovered previously unknown cellular mechanisms involved ...
Jul 1, 2024
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Neuroendocrine tumors, including small cell lung cancer and neuroendocrine prostate cancer, are very aggressive with high chances of spreading. However, many individuals develop resistance to few available treatment options, ...
Jul 3, 2024
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Northwestern Medicine investigators have uncovered how a protein contributes to heart transplant tolerance in mice, according to a study published in the Proceedings of the National Academy of Sciences.
Jul 1, 2024
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Most research in human genetics has historically focused on people of European ancestries—a long-standing bias that may limit the accuracy of scientific predictions for people from other populations.
Jul 17, 2024
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Ribonucleic acid (RNA) is a biologically important type of molecule that consists of a long chain of nucleotide units. Each nucleotide consists of a nitrogenous base, a ribose sugar, and a phosphate. RNA is very similar to DNA, but differs in a few important structural details: in the cell, RNA is usually single-stranded, while DNA is usually double-stranded; RNA nucleotides contain ribose while DNA contains deoxyribose (a type of ribose that lacks one oxygen atom); and RNA has the base uracil rather than thymine that is present in DNA.
RNA is transcribed from DNA by enzymes called RNA polymerases and is generally further processed by other enzymes. RNA is central to the synthesis of proteins. Here, a type of RNA called messenger RNA carries information from DNA to structures called ribosomes. These ribosomes are made from proteins and ribosomal RNAs, which come together to form a molecular machine that can read messenger RNAs and translate the information they carry into proteins. There are many RNAs with other roles – in particular regulating which genes are expressed, but also as the genomes of most viruses.
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