Schizophrenia is a complex disease with variable presentations, and the diverse nature of this mental health disorder has made understanding the mechanisms that cause the disease, and subsequently developing effective treatments, ...
May 23, 2024
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Researchers from the Broad Institute of MIT and Harvard, Harvard Medical School, and McLean Hospital have uncovered a strikingly similar suite of changes in gene activity in brain tissue from people with schizophrenia and ...
Mar 6, 2024
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Genetically speaking, we are individuals different from each other because of slight variations in our DNA sequences—so-called genetic variants—some of which have dramatic effects we can see and comprehend, from the color ...
Sep 15, 2023
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As a psychiatric disorder with onset in adulthood, schizophrenia is thought to be triggered by some combination of environmental factors and genetics, although the exact cause is still not fully understood.
Jul 6, 2023
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More than 100 genes linked to the risk of schizophrenia seem to cause illness because of their role in the placenta rather than in the developing brain, according to a new study led by the Lieber Institute for Brain Development.
May 15, 2023
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Johns Hopkins researchers, along with colleagues in Italy, have published a study in Science Advances that looks into the genetic mechanisms behind the development of schizophrenia.
Researchers at the University of California at Los Angeles have analyzed RNA editing in postmortem brains of four schizophrenia cohorts and uncovered a significant and reproducible trend of hypo-editing in patients of European ...
Researchers have identified two previously unknown genes linked to schizophrenia and newly implicated a third gene as carrying risk for both schizophrenia and autism. Led by the Icahn School of Medicine at Mount Sinai, the ...
Mar 13, 2023
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A team from Nagoya University in Japan used the drug fasudil to reverse two common symptoms associated with schizophrenia: reduced density of pyramidal neurons and cognitive dysfunction associated with methamphetamine treatment. ...
Feb 17, 2023
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Researchers at the University of Pittsburgh School of Medicine, U.S. present the first evidence of 12-hour cycles of gene activity in the human brain. Published in the open access journal PLOS Biology on January 24, the study ...
Jan 24, 2023
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