Researchers have discovered in mice how one of the few genes definitively linked to schizophrenia, called SETD1A, likely confers risk for the illness. Mice genetically engineered to lack a functioning version of the enzyme-coding ...
Oct 24, 2019
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For the first time, scientists have tracked the activity, across the lifespan, of an environmentally responsive regulatory mechanism that turns genes on and off in the brain's executive hub. Among key findings of the study ...
Feb 2, 2012
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An Indiana University-led research team, along with a group of national and international collaborators, has identified and prioritized a comprehensive group of genes most associated with schizophrenia that together can generate ...
May 15, 2012
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The study, published today in Genome Biology and funded by the Medical Research Council, combined genetic sequence information with measures of gene regulation in schizophrenia patients and matched controls.
Aug 29, 2016
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Researchers at Johns Hopkins Medicine report they have identified rare genetic variations in a protein called Thorase, which is responsible for breaking down receptors at the connections between neurons in the brain. By targeting ...
Jan 3, 2018
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Researchers from the Broad Institute of MIT and Harvard, Harvard Medical School, and McLean Hospital have uncovered a strikingly similar suite of changes in gene activity in brain tissue from people with schizophrenia and ...
Mar 6, 2024
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(Medical Xpress) -- Carrying single DNA letter changes from two different genes together may increase the risk of developing schizophrenia, Johns Hopkins researchers reported in the November 16 issue of Neuron.
Dec 16, 2011
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A gene associated with the risk of schizophrenia regulates critical components of early brain development, according to a new study led by researchers from Penn State University. The gene is involved in the translation of ...
Sep 25, 2017
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Johns Hopkins researchers, along with colleagues in Italy, have published a study in Science Advances that looks into the genetic mechanisms behind the development of schizophrenia.
A genetic scoring of schizophrenia-related genes in the placenta can predict the size of a baby's brain at birth and its rate of cognitive development, which, dependent on other factors, may lead to schizophrenia later in ...
Feb 8, 2021
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