Despite the limited supply of organs available for patients on waitlists for transplantation, organs from older, deceased donors are frequently discarded or not utilized. Available older organs have the potential to close ...
Aug 27, 2020
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317
Published in the journal Science, a new study has shed light on a cellular process that occurs in the retinas of people with diabetic retinopathy. This discovery could lead to the development of a treatment for this serious ...
Aug 20, 2020
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155
"Senotherapy," a treatment that uses small molecule drugs to target "senescent" cells, or those cells that no longer undergo cell division, blunts liver tumor progression in animal models according to new research from a ...
May 20, 2020
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99
Scientists at The Wistar Institute discovered a novel pathway that enables detection of DNA in the cytoplasm and triggers inflammation and cellular senescence. This pathway may be modulated during senescence-inducing chemotherapy ...
Feb 19, 2020
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169
Senescent cells, which stop dividing under stress, are long- recognized drivers of multiple diseases of aging. Mouse studies have shown that targeted removal of these cells and the inflammatory factors they secrete, known ...
Jan 16, 2020
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345
In neurodegenerative conditions like Parkinson's disease, a specific group of neurons start to die one by one, causing movement problems and other symptoms. Scientists have long focused on finding out why these neurons die. ...
Nov 11, 2019
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92
Senescence is a cellular stress response that results in the stable growth arrest of old and damaged cells. The past decade has revealed that senescent cells play important roles in a growing list of diseases from cancer, ...
Oct 21, 2019
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137
A new study, published in Aging Cell, has found that human ageing processes may hinder cancer development.
Sep 27, 2019
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281
Cells that become senescent irrevocably stop dividing under stress, spewing out a mix of inflammatory proteins that lead to chronic inflammation as more and more of the cells accumulate over time. Publishing in the September ...
Sep 24, 2019
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109
Call them zombie cells—they refuse to die.
May 15, 2019
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500
