Researchers at Mayo Clinic have shown that senescent cells - cells that no longer divide and accumulate with age - negatively impact health and shorten lifespan by as much as 35 percent in normal mice. The results, which ...
Feb 3, 2016
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S6K1 is a protein involved in the regulation of aging and age-related diseases. Blocking this protein in mice makes them live longer and mimics the health benefits of reducing calorie intake, such as reduced body fat, stronger ...
Aug 29, 2024
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Drugs that selectively kill senescent cells may benefit otherwise healthy older women but are not a "one-size-fits-all" remedy, Mayo Clinic researchers have found. Specifically, these drugs may only benefit people with a ...
Jul 2, 2024
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Researchers at The University of Texas MD Anderson Cancer Center have demonstrated that therapeutically restoring "youthful" levels of a specific subunit of the telomerase enzyme can significantly reduce the signs and symptoms ...
Jun 21, 2024
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A strict "keto-friendly" diet popular for weight loss and diabetes, depending on both the diet and individual, might not be all that friendly.
May 17, 2024
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A form of heart failure that occurs during late pregnancy or early postpartum, peripartum cardiomyopathy (PPCM) is a major cause of maternal death.
Apr 17, 2024
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Diabetes can lead to eye problems, and a common one is diabetic macular edema (DME), causing vision loss. A study published in Nature Medicine suggests a new experimental drug could someday help make treatment of DME more ...
Feb 6, 2024
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Cancer treatments, including chemotherapy, in addition to killing a large number of tumor cells, also result in the generation of senescent tumor cells (also called "zombie cells"). While senescent cells do not reproduce, ...
Jan 24, 2024
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Insights that pave the way for novel therapeutic approaches to tackle cancer, fibrosis, and many age-related conditions have been uncovered by a team of scientists, including researchers from UCL.
Nov 29, 2023
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University of Queensland researchers have found a way to reverse a cellular process triggered by COVID-19 that contributes to premature aging of the brain.
Nov 22, 2023
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