For millennia, malaria has been a major killer of children in Africa and other parts of the world. In doing so, it has been a major force of evolutionary selection on the human genome.
Oct 15, 2014
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An expert panel has created a new evidence-based guideline for managing sickle cell disease (SCD), with a strong recommendation for the use of the drug hydroxyurea and transfusion therapy for many individuals with SCD, although ...
Sep 9, 2014
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Experiencing discrimination because of their race or health condition can influence just how much trust people put into the health profession. In fact, having these experiences was associated with a 53-percent increase in ...
Sep 9, 2014
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Monthly blood transfusions can substantially reduce the risk of recurrent strokes in children with sickle cell disease (SCD) who have already suffered a silent stroke, according to the results of an international study by ...
Aug 20, 2014
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Scientists have altered key biological events in red blood cells, causing the cells to produce a form of hemoglobin normally absent after the newborn period. Because this hemoglobin is not affected by the inherited gene mutation ...
Aug 14, 2014
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Two beneficial variants of a gene controlling red blood cell development have spread from Africa into nearly all human populations across the globe, according to a new study led by King's College London. The international ...
Jul 29, 2014
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Researchers from Salk Institute for Biological Studies, BGI, and other institutes for the first time evaluated the safety and reliability of the existing targeted gene correction technologies, and successfully developed a ...
Jul 11, 2014
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(Medical Xpress)—A compound discovered at Virginia Commonwealth University has taken yet another step closer to becoming the only approved drug in the world that is therapeutically effective in managing adult sickle cell ...
Jul 10, 2014
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The ability to switch out one gene for another in a line of living stem cells has only crossed from science fiction to reality within this decade. As with any new technology, it brings with it both promise—the hope of fixing ...
Jul 9, 2014
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A drug candidate developed by researchers at the NIH's National Center for Advancing Translational Sciences (NCATS) and its collaborators to treat sickle cell disease has been acquired by Baxter International's BioScience ...
Jul 9, 2014
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