Genetics
Why do healthy people have harmful mutations?
"NIH researchers pilot predictive medicine by studying healthy people's DNA," read the headline of a news release yesterday.
Jun 5, 2015
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Page 7 - News tagged with sickle cell gene
Medical research
Researchers show how mutations in 'dark genome' cause pancreatic malformations
Researchers at the Center for Genomic Regulation (CRG) have identified a DNA sequence that is crucial for pancreatic differentiation and function—and for the first time—describe how it works.
Aug 22, 2022
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Medical research
Researchers engineer custom blood cells
Researchers at Johns Hopkins have successfully corrected a genetic error in stem cells from patients with sickle cell disease, and then used those cells to grow mature red blood cells, they report. The study represents an ...
Mar 9, 2015
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Genetics
Research sheds new light on gene therapy for blood disorders
Research from experts at Michigan Medicine, the Children's Hospital of Philadelphia and Penn Medicine is breaking ground on new ways of treating blood disorders, such as sickle cell anemia, through gene therapy. The study ...
Aug 10, 2023
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Medical research
No extra mutations in modified stem cells, study finds
The ability to switch out one gene for another in a line of living stem cells has only crossed from science fiction to reality within this decade. As with any new technology, it brings with it both promise—the hope of fixing ...
Jul 9, 2014
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Diseases, Conditions, Syndromes
Mapping the global burden of sickle cell anaemia
The first rigorous study to assess the global burden of sickle cell anaemia in recent times is reported today in the Lancet, giving an up-to-date view of the distribution of the disease. Accurate estimates of the numbers ...
Oct 25, 2012
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Genetics
Archived Guthrie cards find a new purpose
Over the last 50 years, the spotting of newborn's blood onto filter paper for disease screening, called Guthrie cards, has become so routine that since 2000, more than 90% of newborns in the United States have had Guthrie ...
Aug 22, 2012
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Diseases, Conditions, Syndromes
One day, science may cure sickle cell anaemia
Genetic mutations that affect our blood cells' haemoglobin are the most common of all mutations. It has been estimated that around 5% of the world's population carry a defective globin gene.
Jul 9, 2014
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Medical research
Novel gene-editing therapy continues to show positive results in sickle cell patients
Researchers have presented the latest findings from a clinical trial aimed at discovering a cure for sickle cell disease, a painful genetic blood disorder with limited treatment options.
Jun 15, 2024
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Biomedical technology
US approves sickle cell breakthrough with gene editing therapy
The United States on Friday approved a breakthrough therapy that uses revolutionary gene editing tool CRISPR to treat the debilitating blood disorder sickle cell disease.
Dec 8, 2023
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