Medical research
Gene therapy for blood disorders
Gene therapy holds a lot of promise in medicine. If we could safely alter our own DNA, we might eliminate diseases our ancestors passed down to us.
Nov 27, 2018
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Page 8 - News tagged with sickle cells
Medical research
How sickled red blood cells stick to blood vessels
One of the most common complications of sickle-cell disease occurs when deformed red blood cells clump together, blocking tiny blood vessels and causing severe pain and swelling in the affected body parts.
Sep 3, 2018
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Medical research
Enzyme identified as possible novel drug target for sickle cell disease, Thalassemia
Medical researchers have identified a key signaling protein that regulates hemoglobin production in red blood cells, offering a possible target for a future innovative drug to treat sickle cell disease (SCD). Experiments ...
Jul 19, 2018
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Genetics
New platform poised to be next generation of genetic medicines
A City of Hope scientist has discovered a gene-editing technology that could efficiently and accurately correct the genetic defects that underlie certain diseases, positioning the new tool as the basis for the next generation ...
Jul 16, 2018
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Oncology & Cancer
New genes associated with breast cancer risk
Only a small percentage of breast cancer cases can be linked to heredity, and many of the genes with ties to the disease are unknown.
Jun 26, 2018
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Genetics
Genome-editing tool could increase cancer risk
Therapeutic use of gene editing with the CRISPR-Cas9 technique may inadvertently increase the risk of cancer, according to a new study from Karolinska Institutet, Sweden, and the University of Helsinki, Finland, published ...
Jun 11, 2018
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Medical research
Healthy red blood cells owe their shape to muscle-like structures
Red blood cells are on a wild ride. As they race through the body to deliver oxygen, they must maintain a distinct dimpled shape—and bounce back into form even after squishing through narrow capillaries. Red blood cells ...
Apr 4, 2018
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Genetics
Solution to 50-year-old mystery could lead to gene therapy for common blood disorders
In a landmark study that could lead to new therapies for sickle cell anaemia and other blood disorders, UNSW Sydney-led researchers have used CRISPR gene editing to introduce beneficial natural mutations into blood cells ...
Apr 2, 2018
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Genetics
Genome therapy could lead to new treatment for life-threatening blood disorders
Genome therapy with beneficial natural mutation could lead to new treatment for life-threatening blood disorders
Jul 17, 2017
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Medical research
Gene therapy lets a French teen dodge sickle cell disease
A French teen who was given gene therapy for sickle cell disease more than two years ago now has enough properly working red blood cells to dodge the effects of the disorder, researchers report.
Mar 1, 2017
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