HIV & AIDS

How long have primates been infected with viruses related to HIV?

Disease-causing viruses engage their hosts in ongoing arms races: positive selection for antiviral genes increases host fitness and survival, and viruses in turn select for mutations that counteract the antiviral host factors. ...

Diseases, Conditions, Syndromes

Coadministration of COVID-19, influenza vaccines seems effective

Coadministration of the BNT162b2 BA.4/5 bivalent mRNA COVID-19 vaccine (BNT162b2-biv) and seasonal influenza vaccine (SIV) generally has similar effectiveness against COVID-19- and SIV-related outcomes compared with administration ...

HIV & AIDS

New monkey model for AIDS offers promise for medical research

HIV-1, the virus responsible for most cases of AIDS, is a very selective virus. It does not readily infect species other than its usual hosts – humans and chimpanzees. While this would qualify as good news for most mammals, ...

HIV & AIDS

Replication of immunodeficiency virus in humans

Drs. Beatrice Hahn and Frank Kirchoff led an international research effort to understand what adaptations allow a chimpanzee strain of SIV to replicate in human tissues.

Immunology

In HIV, tissue factor-expressing monocytes trigger coagulation

(HealthDay)—A specific subset of tissue factor (TF)-expressing monocytes persist after virological suppression and trigger the coagulation cascade by activating factor X in HIV, according to a study published online Aug. ...

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