New research on monkeys vaccinated against HIV's relative SIV calls into question an idea that has driven AIDS vaccine work for years. The assumption: a protective vaccine only needs to stimulate moderate levels of antibodies ...
Aug 11, 2015
0
44
Beatrice H. Hahn, MD, a professor of Medicine and Microbiology in the Perelman School of Medicine at the University of Pennsylvania, and her colleagues have been studying the origin of HIV-1 in non-human primates for decades. ...
Feb 4, 2019
0
70
Some monkeys can survive infection by SIV, a relative of HIV, and not develop AIDS. Their immune systems appear to display a pattern of "peaceful coexistence" rather than the all-out conflict provoked by HIV when it infects ...
Mar 8, 2012
0
0
Viruses known as gammaherpesviruses may raise the risk of cancer in macaques infected with Simian Immunodeficiency Virus or Simian Human Immunodeficiency Virus (SIV/SHIV), according to new research published by Vickie Marshall ...
Jul 12, 2018
0
16
The most critical barrier for curing HIV-1 infection is the presence of the viral reservoir, the cells in which the HIV virus can lie dormant for many years and avoid elimination by antiretroviral drugs. Very little has been ...
Jul 20, 2014
0
0
One of the challenges to HIV vaccine development has been the lack of an animal model that accurately reflects the human immune response to the virus and how the virus evolves to evade that response. In the July 18 issue ...
Jul 18, 2012
0
0
After being infected with simian immunodeficiency virus (SIV) in a laboratory study, rhesus macaques that had more of a certain type of immune cell in their gut than others had much lower levels of the virus in their blood, ...
May 30, 2012
0
0
Scientists at the National Institutes of Health have found that the presence of the protein alpha-4 beta-7 integrin on the surface of HIV and its monkey equivalent—simian immunodeficiency virus, or SIV—may help explain ...
Feb 15, 2017
0
16
A collaborative effort between investigators at the Yerkes National Primate Research Center, Emory University School of Medicine and Georgia Institute of Technology has led to the development of a non-invasive method to image ...
Mar 9, 2015
0
12
According to the WHO, there are currently more than 36 million people infected with the human immunodeficiency virus (HIV) and a further 2.4 million become infected every year. Despite treatment success against the virus, ...
Nov 16, 2017
0
12
