Obstetrics & gynaecology

Pregnancy outcomes greatly improved in lupus patients

Historically, pregnancy in patients with systemic lupus erythematosus (SLE) was considered so risky that physicians counseled women to avoid becoming pregnant and recommended that women carrying a child terminate their pregnancy. ...

Arthritis & Rheumatism

Researchers reveal how receptor TLR-9 protects against lupus

When the pathogen-sensing intracellular receptors TLR-7 and TLR-9 were implicated in systemic lupus erythematosus (SLE), it was suspected that their removal would lessen the severity of the disease. However, while this held ...

Genetics

How a single faulty gene can lead to lupus

A research team at the Academy of Immunology and Microbiology, within the Institute for Basic Science (IBS) & Pohang University of Science and Technology (POSTECH) in South Korea has discovered the role of a key gene involved ...

Immunology

Researchers use blood serum markers to develop lupus risk index

Researchers at the Feinstein Institute for Medical Research, USA have developed an index that identifies the risk for lupus based on the presence and amount of Immunoglobin G (IgG) and Immunoglobin M (IgM) antibodies and ...

Alzheimer's disease & dementia

Lupus linked with increased risk of dementia

A new International Journal of Geriatric Psychiatry study indicates that the risk of dementia may be elevated in individuals with systemic lupus erythematosus (SLE), an autoimmune disease affecting a range of systems including ...

Immunology

Genetic risk for lupus tied to ancestry

Northwestern Medicine collaborated with international colleagues in a study that identified two dozen new genes linked to lupus after analyzing genetic samples from over 27,000 individuals across the globe.

Arthritis & Rheumatism

Alterations in soluble mediators predict transition to SLE

(HealthDay)—For unaffected relatives of systemic lupus erythematosus (SLE) patients, preclinical alterations in levels of soluble mediators may predict transition to disease, according to a study published in the March ...

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