Mutations in the SCN3A gene cause a spectrum of neurological conditions collectively referred to as SCN3A-related neurodevelopmental disorders, which includes different types of epilepsy and brain malformations.
Nov 21, 2023
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Researchers at NYU College of Dentistry's Pain Research Center have developed a gene therapy that treats chronic pain by indirectly regulating a specific sodium ion channel, according to a new study published in the Proceedings ...
Jul 27, 2023
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The behavioral disorders observed in autism are associated with a multitude of genetic alterations. Scientists from the Hector Institute for Translational Brain Research (HITBR) have now found another molecular cause for ...
Feb 13, 2023
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People with chronic epilepsy often experience impaired memory. Researchers at the University of Bonn have now found a mechanism in mice that could explain these deficits. The German Center for Neurodegenerative Diseases (DZNE) ...
Dec 19, 2022
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Therapeutically targeting ion channels in nociceptor neurons may be a promising strategy to manage osteoarthritis pain, according to a Northwestern Medicine study published in Cell Reports.
Oct 5, 2022
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In recent years, cannabidiol, a compound derived from cannabis plants, has begun popping up more and more in everyday life. Now legal in most U.S. states, the cannabinoid commonly known as CBD can be found in supermarkets ...
Jul 15, 2022
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Ion channels, which allow potassium and sodium ions to flow in and out of cells, are crucial in neuronal 'firing' in the central nervous system and for brain and heart function. These channels use a "ball-and-chain" mechanism ...
Mar 18, 2020
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Finnish researchers have found cellular components in the epithelial tissue of the eye, which have previously been thought to only be present in electrically active tissues, such as those in nerves and the heart. A study ...
Aug 15, 2019
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Johns Hopkins Medicine researchers recently found a key structural differences in channels that regulate how and when heart and skeletal muscles contract. Identifying the differences between the two, say researchers, provides ...
May 15, 2019
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Researchers have discovered a "missing mutation" in severe infant epilepsy—long-suspected genetic changes that might trigger overactive, brain-damaging electrical signaling leading to seizures They also found early indications ...
Mar 20, 2018
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