Researchers at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) and the Instituto de Investigación Sanitaria Princesa (IIS Princesa) have made a major advance toward deciphering the mechanism through which ...
Jul 29, 2020
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(Medical Xpress)—A large team of European researchers has identified a gene mutation that is responsible for causing a condition that leads to an inability to experience pain in humans. In their paper published in Nature ...
Dravet syndrome is a rare and severe form of epilepsy caused primarily by inherited loss-of-function mutations in a gene called SCN1A. This gene encodes a sodium ion channel known as Nav1.1 and is required for the proper ...
Sep 20, 2013
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For years, a multidisciplinary team of Johns Hopkins researchers has tracked an elusive creature, a complex of proteins thought to be at fault in some cases of sudden cardiac death. As they report Nov. 5 in the online edition ...
Nov 5, 2014
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Ion channels, which allow potassium and sodium ions to flow in and out of cells, are crucial in neuronal 'firing' in the central nervous system and for brain and heart function. These channels use a "ball-and-chain" mechanism ...
Mar 18, 2020
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In epilepsy, nerve cells lose their usual rhythm, and ion channels, which have a decisive influence on their excitability, are involved. A team of researchers under the direction of the University of Bonn has now discovered ...
Nov 19, 2015
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Scientists have solved a longstanding mystery of the central nervous system, showing how a key protein gets to the right spot to launch electrical impulses that enable communication of nerve signals to and from the brain.
Jan 9, 2014
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Duke University researchers have found an antibody that simultaneously blocks the sensations of pain and itching in studies with mice.
May 22, 2014
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The gold standard test for predicting the onset of diabetic kidney disease is the albuminuria test. However, detecting albuminuria alone has limited sensitivity and specificity in end-stage renal failure with a decreased ...
Jun 13, 2023
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Abnormalities in the proteins responsible for transmitting electrical signals in the heart likely cause abnormal heart rhythms in patients with Duchenne muscular dystrophy (DMD), shows a study published in eLife.
Jun 28, 2022
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