Medications

Statin use associated with increased survival in severe COVID-19

People who took statins to lower cholesterol were approximately 50% less likely to die if hospitalized for COVID-19, a study by physicians at Columbia University Vagelos College of Physicians and Surgeons and NewYork-Presbyterian ...

Medications

Trial finds no overall effect of statins on muscle pain

A trial published by The BMJ today finds no overall effect of statins on the frequency or severity of muscle symptoms compared with placebo in people who had previously reported severe muscle symptoms when taking statins.

Cardiology

Study examines aspirin and statin use among older Americans

An analysis published in the Journal of the American Geriatrics Society indicates that while adults aged 75 years and older do not benefit from taking aspirin to prevent cardiovascular disease, many do so on a regular basis. ...

Medications

Could we use statins to treat COVID-19?

Nothing in medicine is as exciting as discovering new drugs. However, this process is time consuming, expensive and not always necessary. Sometimes, existing drugs can be used to manage illnesses that are different to those ...

Cardiology

Statins can save lives, are they being used?

People who have coronary artery disease, stroke or peripheral artery disease often are prescribed a statin, a cholesterol-lowering drug that reduces the risk of heart attack or stroke.

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Statin

The statins (or HMG-CoA reductase inhibitors) are a class of drugs that lower cholesterol levels in people with or at risk of cardiovascular disease.

They lower cholesterol by inhibiting the enzyme HMG-CoA reductase, which is the rate-limiting enzyme of the mevalonate pathway of cholesterol synthesis. Inhibition of this enzyme in the liver results in decreased cholesterol synthesis as well as increased synthesis of LDL receptors, resulting in an increased clearance of low-density lipoprotein (LDL) from the bloodstream. The first results can be seen after one week of use and the effect is maximal after four to six weeks.

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