St. Jude Children's Research Hospital scientists have discovered evidence of a mechanism at the heart of amyotrophic lateral sclerosis (ALS) and related degenerative diseases. The research appears in today's edition of the ...
Sep 24, 2015
0
14
Researchers at the Francis Crick Institute have found that cellular structures called stress granules perform an essential protective function in support of the immune response against infections like tuberculosis (TB).
Nov 21, 2023
0
36
The same signal that drives aggressive growth in a deadly cancer cell type also triggers coping mechanisms that make it "notoriously" hard to kill, according to a study published online December 15 in Cell. When stressed, ...
Dec 15, 2016
0
3
J. Gavin Daigle, a PhD candidate at the LSU Health New Orleans School of Graduate Studies, is the first author of a paper whose findings reveal another piece of the Amyotrophic Lateral Sclerosis (ALS) puzzle. Working with ...
Jan 19, 2016
0
76
Under normal circumstances, tau protein is part of the brain's infrastructure, important for stabilizing neurons into their proper shapes. But sometimes tau gets knotted up into tangles and turns toxic, injuring brain tissue ...
Sep 21, 2023
0
76
A new research paper was published on the cover of Aging, title "Stress granules sequester Alzheimer's disease-associated gene transcripts and regulate disease-related neuronal proteostasis."
Jun 1, 2023
0
11
St. Jude Children's Research Hospital scientists have found that the enzymes ULK1 and ULK2 play a key role in breaking down cell structures called stress granules, whose persistence leads to toxic buildup of proteins that ...
Apr 10, 2019
0
0
Amyotrophic lateral sclerosis, better known as Lou Gehrig's disease, is a devastating illness that gradually robs sufferers of muscle strength and eventually causes a lethal, full-body paralysis. The only drug available to ...
Dec 16, 2013
0
0
Our bodies contain a special protein tag that plays a role in how cells recover from specific threats to their survival, according to new research I co-authored. Understanding how this process works may be key to future treatments ...
Jun 25, 2021
0
2
