Neuroscience

Researchers discover fundamental pathology behind ALS

A team led by scientists at St. Jude Children's Research Hospital and Mayo Clinic has identified a basic biological mechanism that kills neurons in amyotrophic lateral sclerosis (ALS) and in a related genetic disorder, frontotemporal ...

Genetics

Scientists identify ALS disease mechanism

Researchers have tied mutations in a gene that causes amyotrophic lateral sclerosis (ALS) and other neurodegenerative disorders to the toxic buildup of certain proteins and related molecules in cells, including neurons. The ...

Alzheimer's disease & dementia

Researchers describe new biology of Alzheimer's disease

In a new study, researchers from Boston University School of Medicine (BUSM) describe a unique model for the biology of Alzheimer's disease (AD) which may lead to an entirely novel approach for treating the disease. The findings ...

Oncology & Cancer

Stress granules may drive obesity-associated pancreatic cancer

Obesity is a known risk factor for at least 13 types of cancer, in part because it creates ever-present inflammatory state. For years, one researcher has wondered if there's more to the story than inflammation. New research ...

Oncology & Cancer

Stress granules ease the way for cancer metastasis

Tumors that produce more stress granules are more likely to metastasize, according to a study published in The Journal of Cell Biology. The results suggest that drugs to inhibit the formation of these structures might rein ...

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