Dementia with Lewy bodies (DLB), one of the most common forms of dementia, has no cure. Previous studies suggested that gut bacteria, the microorganisms that live in the human digestive tract, play a role in Parkinson's disease, ...
Mar 1, 2023
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In a largely neglected brain region, scientists identified neurons that produce the stress hormone CRH (corticotropin-releasing hormone). They showed that the CRH produced in this region plays a role in behavioral arousal, ...
Nov 25, 2022
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Northwestern Medicine investigators have discovered that dopaminergic neurons in the substantia nigra utilize a specific ion channel to meet anticipated energy needs, according to findings published in Science Advances.
Oct 20, 2022
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Scientists have uncovered how dopamine connects subregions of the striatum essential for habit formation, according to a Northwestern Medicine study published in Cell Reports, findings that may change the overall understanding ...
Aug 25, 2022
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A team of neurophysicists, led by Malte Brammerloh of MPI CBS, found evidence that the identification of a magnetic resonance imaging (MRI) sign for Parkinson's diagnosis, as a specific anatomical region in the brain, is ...
Aug 17, 2022
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There is currently no cure for Parkinson's disease (PD), and one of the main difficulties for developing treatments is that we don't know exactly how or why the disease occurs. It's generally believed that a buildup of Lewy ...
Jul 5, 2022
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A team of researchers affiliated with several institutions in the U.S. has identified a subtype of brain cells that die in Parkinson's patients. In their study, published in the journal Nature Neuroscience, the group used ...
A novel system to control protein aggregation in a model of Parkinson's disease may answer longstanding questions about how the disease begins and spreads, according to a new study published March 9 in the open-access journal ...
Mar 22, 2022
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Northwestern investigators have discovered the molecular signature of a subset of dopaminergic neurons with an increased vulnerability to degeneration.
Dec 13, 2021
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In late-stage Parkinson's disease, the drug levodopa becomes less effective in treating symptoms because of the inexorable loss of dopamine-releasing neurons. But a new Northwestern Medicine preclinical study shows a gene ...
Nov 3, 2021
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