For many inherited diseases, such as cystic fibrosis or Huntington disease, the disease-causing genetic mutation damages or removes a protein that has an essential role in the body. This protein defect is the root cause of ...
Aug 8, 2013
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Using new methodology, University of Kentucky researchers have mapped the variations in sugar chains attached to brain proteins from deceased healthy individuals or individuals with Alzheimer's disease.
Dec 16, 2021
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Antibodies are the foot soldiers of our immune system. These specialized, Y-shaped proteins attach to bacteria and viruses, where they either block the pathogen's activity directly, or signal the immune system's cells to ...
Mar 13, 2017
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Recently, a grassroots effort initiated by families and clinicians led to the discovery of a human genetic disorder with severe consequences that is linked to a mutation in the human NGLY1 gene. In a big step towards understanding ...
Jan 19, 2015
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The same protein tells beta cells in the pancreas to stop making insulin and then to self-destruct as diabetes worsens, according to a University of Alabama at Birmingham (UAB) study published online today in the journal ...
Aug 26, 2013
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(Medical Xpress)—Researchers under ETH-Zurich professor Martin Fussenegger have created a new genetic network that could cure the various symptoms of so-called metabolic syndrome in one fell swoop. It already works in mice.
Dec 18, 2012
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Researchers at the University of Iowa have worked out the exact function of an enzyme that is critical for normal muscle structure and is involved in several muscular dystrophies. The findings, which were published Jan. 6 ...
Jan 9, 2012
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Researchers have uncovered exactly how a human egg captures an incoming sperm to begin the fertilisation process, in a new study published this week in the journal Science.
Aug 18, 2011
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New research from UBC Okanagan could make monitoring gut health easier and less painful by tapping into a common—yet often overlooked—source of information: the mucus in our digestive system that eventually becomes part ...
Feb 13, 2024
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A cytokine named TRAIL binds to TRAIL receptors and kills cancer cells, but not normal cells. Various anticancer drugs targeting TRAIL receptors have been developed and gained great attention as a promising cancer therapeutics, ...
Aug 15, 2022
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