The development of effective anti-androgen therapies for prostate cancer is a major scientific advance. However, some men who receive these targeted treatments are more likely to develop a deadly treatment-resistant prostate ...
Feb 28, 2019
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36
In a recent paper in Science Signaling, associate professor of cell and microbiology Carla Finkielstein, of the Department of Biological Sciences, and her collaborators identified an alternative mechanism to control circadian ...
Feb 4, 2019
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223
While many cells in our bodies can accumulate oncogenic mutations, the majority of these events do not lead to tumor formation as these abnormal cells are eliminated by defense mechanisms. Instead, tumors arise when a mutation ...
Nov 28, 2018
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137
Chess and cancer research have one thing in common: It takes strategy to defeat the opponent. And that's exactly what scientists at the MDC are doing. They are seeking to selectively make only those cancer cells aggressive ...
Nov 28, 2018
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51
B cells are important in helping the immune system fight pathogens. However, in the case of the neurological autoimmune disease multiple sclerosis (MS), they can damage nerve tissue. When particular control cells are missing, ...
Nov 9, 2018
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87
Researchers at The Wistar Institute have characterized the function of neutrophils, a type of white blood cells, during early stages of tumor progression, showing that they migrate from the bone marrow to distant sites and ...
Oct 15, 2018
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77
A little p63 goes a long way in embryonic development—and flaws in p63 can result in birth defects like cleft palette, fused fingers or even missing limbs. But once this early work is done, p63 goes silent, sitting quietly ...
Sep 18, 2018
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36
Investigators at Children's Hospital Los Angeles have been able to pinpoint the exact stage of development of the human retina, when cells can grow out of control and form cancer-like masses. The finding could open the door ...
Sep 14, 2018
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178
Researchers at The University of Texas MD Anderson Cancer Center have shown how BRCA-associated protein 1 (BAP1) serves as a tumor suppressor gene in kidney, eye, bile duct, mesothelioma and other cancers by regulating a ...
Sep 10, 2018
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17
The PLK1 gene, which has for decades been considered a tumor promoter, can also halt the development of cancer. This finding was made by researchers from the Spanish National Cancer Research Centre (CNIO) and Germany's Cancer ...
Aug 8, 2018
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