Oncology & Cancer

Anti-cancer effects found in natural compound derived from onions

Research from Kumamoto University, Japan finds that a natural compound isolated from onions, onionin A (ONA), has several anti-cancer properties for ovarian cancer. This discovery is a result of research on the effects of ...

Genetics

Regulatory RNA essential to DNA damage response

Stanford researchers have found that a tumor suppressor known as p53 is stabilized by a regulatory RNA molecule called DINO. The interaction helps a cell respond to DNA damage and may play a role in cancer development and ...

Immunology

Scientists identify marker for myeloid-derived suppressor cells

Myeloid-derived suppressor cells (MDSCs) are a population of immune cells that have been implicated in tumor resistance to various types of cancer treatment, including targeted therapies, chemotherapy and immunotherapy. Polymorphonuclear ...

Medical research

Brad Pitt's and fruit flies' cowlicks controlled by cancer protein

What does Brad Pitt have in common with a fruit fly? His Hollywood hairstyles cover a prominent cowlick - the swirl of hair that that is caused by a patterning mechanism also active in our two-winged friends—that similarly ...

Oncology & Cancer

Scientists show how cancerous cells evade a potent targeted therapy

Imagine developing a drug designed to inhibit a protein that helps cancer cells proliferate and survive only to find that the drug does not perform very well in the clinic. This was the dilemma faced by scientists researching ...

Oncology & Cancer

A cancer's surprise origins, caught in action

Researchers at Boston Children's Hospital have, for the first time, visualized the origins of cancer from the first affected cell and watched its spread in a live animal. Their work, published in the January 29th issue of ...

Genetics

New class of RNA tumor suppressors identified

A pair of RNA molecules originally thought to be no more than cellular housekeepers are deleted in over a quarter of common human cancers, according to researchers at the Stanford University School of Medicine. Breast cancer ...

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