The Telomeres and Telomerase Group at the Spanish National Cancer Research Centre (CNIO), in collaboration with the Centre's Transgenic Mice Core Unit, has succeeded in creating mice in the laboratory with hyper-long telomeres ...
Jun 2, 2016
0
1120
Making a drug is like trying to pick a lock at the molecular level. There are two ways in which you can proceed. You can try thousands of different keys at random, hopefully finding one that fits. The pharmaceutical industry ...
Apr 26, 2018
0
69
Researchers have revealed how a molecule called telomerase contributes to the control of the integrity of our genetic code, and when it is involved in the deregulation of the code, its important role in the development of ...
Dec 8, 2011
0
0
The human body is essentially made up of trillions of living cells. It ages as its cells age, which happens when those cells eventually stop replicating and dividing. Scientists have long known that genes influence how cells ...
Jul 23, 2021
1
198
A mutation that helps make cells immortal is critical to the development of a tumor, but new research at the University of California, Berkeley suggests that becoming immortal is a more complicated process than originally ...
Aug 17, 2017
0
122
Researchers at UT Southwestern Medical Center have found that alternative splicing – a process that allows a single gene to code for multiple proteins – appears to be a new potential target for anti-telomerase cancer ...
Apr 19, 2013
0
0
Researchers have identified a gene that when inhibited or reduced, in turn, reduced or prevented human non-small cell lung cancer tumors from growing.
Aug 6, 2018
0
38
Researchers at the University of Louisville's James Graham Brown Cancer Center have identified for the first time mutations that destabilize a DNA structure that turns a gene off. These mutations occur at four specific sites ...
Dec 22, 2014
0
0
Idiopathic pulmonary fibrosis is a potentially lethal disease associated with the presence of critically short telomeres, currently lacking effective treatment. The Telomere and Telomerase Group at the Spanish National Cancer ...
Jan 30, 2018
0
57
The enzyme telomerase repairs cell damage produced by ageing, and has been used successfully in therapies to lengthen the life of mice. Now it has been observed that it could also be used to cure illnesses related to the ...
Dec 18, 2014
0
0
