No one likes the thought of getting old, but it seems to be an inevitable part of life. Most species grow, develop and repair damage to their bodies until a certain point in adulthood. After this, the body becomes less capable ...
Sep 20, 2022
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Switching off the enzyme that adds protective caps to chromosome ends could help fight many types of cancer, A*STAR researchers have shown. The team demonstrated the treatment's potential by using it to thwart tumor growth ...
Dec 20, 2018
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A study of DNA rearrangements in roundworm chromosomes may offer new insight into large-scale genome duplications that occur in developing tumors.
Apr 21, 2011
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Researchers have identified a gene that when inhibited or reduced, in turn, reduced or prevented human non-small cell lung cancer tumors from growing.
Aug 6, 2018
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Like a car's front and back bumpers, your cell's chromosomes are capped by "telomeres" that protect this genetic material against deterioration. Still, after enough replications, a chromosome's telomeres break down and once ...
Feb 18, 2015
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Researchers at the University of Louisville's James Graham Brown Cancer Center have identified for the first time mutations that destabilize a DNA structure that turns a gene off. These mutations occur at four specific sites ...
Dec 22, 2014
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Idiopathic pulmonary fibrosis is a potentially lethal disease associated with the presence of critically short telomeres, currently lacking effective treatment. The Telomere and Telomerase Group at the Spanish National Cancer ...
Jan 30, 2018
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Although neuroendocrine tumors of the pancreas are rare, the available treatment options are currently limited. Researchers have now managed to identify the mutation mechanism, namely a mutation on the gene that activates ...
Jul 16, 2020
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Stem cells are among the most energetically activated, migratory and proliferative sub-populations of tumour cells, according to observations by scholars at the Biomedical Research Centre at the University of Salford.
Jan 18, 2017
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(Medical Xpress)—Yale School of Medicine and Yale Cancer Center researchers have uncovered a genetic vulnerability of cancer cells that express telomerase—an enzyme that drives their unchecked growth—and showed that ...
Jul 18, 2014
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