Scientists have discovered a new function for a protein that protects cells during injury and could eventually translate into treatment for conditions ranging from cardiovascular disease to Alzheimer's.
Jun 7, 2012
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Researchers have demonstrated the feasibility of delivering an RNA that encodes for the protein alpha-1-antitrypsin (AAT)—which is missing or nonfunctional in the genetic disorder AAT deficiency—into cells in the laboratory, ...
Jul 27, 2015
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Researchers from the Institute of Neuroscience and their collaborators have revealed a new cellular mechanism for amyotrophic lateral sclerosis (ALS), suggesting a novel therapeutic strategy targeting the RNA degradation ...
Apr 9, 2019
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Rheumatoid arthritis (RA) is a debilitating autoimmune disorder that is characterized by the accumulation of inflammatory cells within the fluid of the joints. Current therapeutic strategies mostly serve to ease pain and ...
Apr 21, 2016
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Researchers at Moffitt Cancer Center and colleagues have demonstrated that the inhibition of signal transducer and activator of transcription 3 (STAT3) in mouse models of mantle cell lymphoma (MCL), an aggressive and incurable ...
Jul 18, 2012
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Scientists may have discovered why a protein called MYC can provoke a variety of cancers. Like many proteins associated with cancer, MYC helps regulate cell growth. A study carried out by researchers at the National Institutes ...
Sep 27, 2012
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Adhering closely to Darwin's theory of evolution, tumors need to adapt to environmental changes to survive. A new study shows that one of those changes—the compression of cells—can both help and hinder the progression ...
Sep 25, 2023
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(Medical Xpress)—Researchers at the Moffitt Cancer Center have found that delayed tumor growth and enhanced survival of mice bearing melanoma were possible by blocking the reconstitution of myeloid-derived suppressor cells ...
Dec 11, 2012
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A new study from Tel Aviv University suggests that early clues about the progression of the disease can be found in the metabolism of the brain, making it possible to detect and diagnose Alzheimer's at an early stage with ...
Nov 7, 2012
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The fixed combination of canagliflozin with metformin (trade name: Vokanamet) has been approved since April 2014 for adults with type 2 diabetes mellitus in whom diet and exercise do not provide adequate glycaemic control. ...
Nov 21, 2014
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