Trophoblast cells, which surround the developing blastocyst in early pregnancy, play an important role in implantation in the uterine wall. A new multidimensional model of trophoblast motility that utilizes a functionalized ...
Dec 23, 2020
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Researchers at the University of Pittsburgh School of Medicine have combined synthetic biology with a machine-learning algorithm to create human liver organoids with blood- and bile-handling systems. When implanted into mice ...
Dec 07, 2020
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Using a new technique, a team of McGill University researchers has found tiny and previously undetectable 'hot spots' of extremely high stiffness inside aggressive and invasive breast cancer tumors. Their findings suggest, ...
Oct 27, 2020
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Short fragments of cell-free DNA (cfDNA) that circulate in blood, urine, and other biofluids can offer an information-rich window into human physiology and disease. By looking at the methylation markers of cfDNA, researchers ...
Oct 26, 2020
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In laboratory studies, Johns Hopkins Kimmel Cancer Center and Johns Hopkins University researchers observed a key step in how cancer cells may spread from a primary tumor to a distant site within the body, a process known ...
Sep 01, 2020
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When it comes to training neural circuits for tissue engineering or biomedical applications, a new study suggests a key parameter: Train them young.
Aug 06, 2020
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Scientists from Nanyang Technological University, Singapore (NTU Singapore) and the Agency for Science, Technology and Research (A*STAR) have shown that applying 'temporal pressure' to the skin of mice can create a new way ...
Aug 04, 2020
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In the TV series Westworld, human body parts are built on robotic frames using 3-D printers. While still far from this scenario, 3-D printers are being increasingly used in medicine. For example, 3-D printing can be used ...
Jun 15, 2020
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Tissue engineering has a unique set of tools and technologies for developing preventive strategies, diagnostics, and treatments that can play an important role during the ongoing COVID-19 pandemic. Three key areas pioneered ...
May 08, 2020
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In the quest to engineer replacement tissues and organs for improving human health, biofabrication has emerged as a crucial set of technologies that enable the control of precise architecture and organization. A new article ...
Apr 29, 2020
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Tissue engineering was once categorised as a subfield of Biomaterials, but having grown in scope and importance it can be considered as a field in its own right. It is the use of a combination of cells, engineering and materials methods, and suitable biochemical and physio-chemical factors to improve or replace biological functions. While most definitions of tissue engineering cover a broad range of applications, in practice the term is closely associated with applications that repair or replace portions of or whole tissues (i.e., bone, cartilage, blood vessels, bladder, etc.). Often, the tissues involved require certain mechanical and structural properties for proper functioning. The term has also been applied to efforts to perform specific biochemical functions using cells within an artificially-created support system (e.g. an artificial pancreas, or a bioartificial liver). The term regenerative medicine is often used synonymously with tissue engineering, although those involved in regenerative medicine place more emphasis on the use of stem cells to produce tissues.
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