Mutations in the MAGEL2 gene, which cause Schaaf-Yang syndrome (SYS)—an ultra-rare disease that affects neuronal and cognitive development—generate truncated, non-functional proteins that tend to accumulate in the cell ...
May 7, 2024
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Alzheimer's disease is the most common form of dementia, affecting over 35 million people worldwide. It is generally assumed that the clumping of beta-amyloid (Aß) protein causes neuronal loss in patients. Medication focuses ...
Dec 14, 2012
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Second- or third-line treatment with tisotumab vedotin is efficacious for patients with recurrent cervical cancer, according to a study published in the New England Journal of Medicine.
Jul 8, 2024
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Scientists at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) have identified the mechanisms through which anthracyclines, a widely used class of anticancer drugs, damage the hearts of patients receiving this ...
Apr 16, 2024
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After showing promise in early laboratory research, the cholesterol-lowering drug fenofibrate had no significant effect on COVID-19 outcomes in a multicenter international randomized clinical trial led by Penn Medicine scientists. ...
Nov 7, 2022
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A new treatment for chronic constipation may bring relief without having to use drugs.
Feb 10, 2023
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Although the innate immune system is the front line of defense against microbial infections, the complex mechanisms of innate immunity are incompletely understood. In a new study, researchers from Kanazawa University synthesized ...
Jun 23, 2020
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Researchers have identified a protein that, when targeted, enables cisplatin-resistant cancer cells to become responsive to treatment. Cisplatin, and other similar platinum drugs, are incredibly effective at killing rapidly ...
Mar 27, 2024
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Looking for a cold remedy at your local pharmacy? Be careful what you choose: experts warn that some options on the shelves may be no better than sugar pills.
Feb 2, 2023
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Higher lead levels in a mother's blood can increase the chance of her bearing male offspring, according to new research led by Japanese scientists at the Tohoku University Graduate School of Medicine.
Mar 14, 2022
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