A new study, led by researchers from the University of California, Irvine (UCI), uncovers the long-sought-after, three-dimensional structure of a toxin primarily responsible for devastating Clostridium difficile infection ...
Jul 15, 2019
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20
Researchers have identified a compound that strongly inhibits botulinum neurotoxin, the most toxic compound known. That inhibiting compound, nitrophenyl psoralen (NPP), could be used as a treatment to reduce paralysis induced ...
Nov 2, 2018
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424
Every year, millions of people have vacations and business trips ruined when they succumb to "traveler's diarrhea" during their journeys. A major cause of traveler's diarrhea is bacteria called Enterotoxigenic E. coli, or ...
Sep 25, 2018
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38
A modified form of botulinum toxin gives long-lasting pain relief in mice without adverse effects and, in time, could replace opioid drugs as a safe and effective way of treating chronic pain, according to research by UCL, ...
Jul 18, 2018
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92
NC State researchers developed a drug-testing pipeline to help identify compounds that worked against the three stages of Clostridium difficile infection, and found that a compound that holds promise for treating antibiotic-resistant ...
Jun 28, 2018
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198
New research has uncovered a surprise link between a common bacterial toxin found in the gut and inflammatory bowel disease (IBD).
May 17, 2018
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1240
Researchers from the University of California, Irvine and Harvard University have discovered how the Clostridium difficile toxin B (TcdB) recognizes the human Frizzled protein, the receptor it uses to invade intestinal cells ...
May 11, 2018
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69
A research team led by Ana Domingos, from Instituto Gulbenkian de Ciencia (IGC; Portugal) has developed a new genetic technique that eliminates specific neurons of the peripheral nervous system without affecting the brain. ...
Apr 3, 2017
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160
In a study that could have significant impact on how disease outbreaks are managed, researchers at UC Davis and the California Department of Public Health (CDPH) have sequenced and analyzed genomes from Shigella sonnei (S. ...
Dec 23, 2016
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22
Researchers have identified a key target in fighting the emerging, life-threatening gastrointestinal infection Clostridium difficile. The work, led by Min Dong, PhD, and Liang Tao, PhD, of Boston Children's Hospital, reveals ...
Sep 29, 2016
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19
