Oncology & Cancer
Newly defined cancer driver is fast, furious and loud
The Fast and the Furious movie franchise meets the Fast N' Loud television series to define an oncogene that drives 35% of prostate cancers.
Jun 26, 2019
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Page 12 - News tagged with transcription factors
Cardiology
Converting scar tissue to heart muscle after a heart attack
It is estimated that during a heart attack, one billion cells in the heart are lost. In the wake of the heart attack, the lost tissue is replaced by scar tissue, which can lead to heart failure, arrhythmia and death. In a ...
Jun 2, 2021
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Oncology & Cancer
Old drugs bring new hope to a cancer that lacks precision therapy
An estimated 15 to 20 percent of all breast cancer patients are "triple negative." These unfortunate women lack three crucial treatment targets—the estrogen receptor, the progesterone receptor and human epidermal growth ...
Mar 6, 2019
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Immunology
How to become a T follicular helper cell
Follicular helper Tcells (TFH cells), a rare type of immune cell that is essential for inducing a strong and lasting antibody response to viruses and other microbes, have garnered intense interest in recent years but the ...
Jul 30, 2015
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Oncology & Cancer
Researchers identify protein linked to metastasis in pancreatic cancer
Pancreatic cancer is the No. 3 cause of cancer-related deaths in the United States, and only 12% of patients survive five years after being diagnosed. Severe pancreatic cancer is associated with metastasis, and it is this ...
Feb 3, 2024
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Genetics
How glial cells develop in the brain from neural precursor cells
Two types of cells are active in the brain: nerve cells and glial cells. Glial cells have long been regarded primarily as supportive cells, but researchers increasingly recognize that they play an active role in the communication ...
Dec 11, 2018
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Genetics
SUMO-snipping protein plays crucial role in T and B cell development
When SUMO grips STAT5, a protein that activates genes, it blocks the healthy embryonic development of immune B cells and T cells unless its nemesis breaks the hold, a research team led by scientists at The University of Texas ...
Jan 27, 2012
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Neuroscience
Two heads are better than one: Gene expression reveals molecular mechanisms underlying evolution of cerebral cortex
Dramatic expansion of the human cerebral cortex, over the course of evolution, accommodated new areas for specialized cognitive function, including language. Understanding the genetic mechanisms underlying these changes, ...
Nov 9, 2012
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Alzheimer's disease & dementia
A 'switch' in Alzheimer's and stroke patient brains that prevents the generation and survival of neurons
A new study by researchers at Sanford-Burnham Medical Research Institute (Sanford-Burnham) has identified a chemical "switch" that controls both the generation of new neurons from neural stem cells and the survival of existing ...
Jul 3, 2014
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Medical research
The role of metabolic signaling in preventing atrial fibrillation
Research from the Yale School of Medicine indicates that a protein kinase that is a master regulator of cell metabolism is critical to preventing atrial fibrillation. The research appeared April 22 in the journal JCI Insight.
Apr 26, 2022
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