Obstetrics & gynaecology

Preeclampsia triggered by an overdose of gene activity

Preeclampsia is the most dangerous form of hypertension during a pregnancy and can be fatal for both mother and child. Though it is known to originate in the placenta, the root causes remain largely a mystery. An international ...

Oncology & Cancer

Prostaglandin E1 inhibits leukemia stem cells

Two drugs, already approved for safe use in people, may be able to improve therapy for chronic myeloid leukemia (CML), a blood cancer that affects myeloid cells, according to results from a University of Iowa study in mice.

Oncology & Cancer

A new paradigm for treating transcription factor-driven cancers

In the current issue of Proceedings of the National Academy of Sciences, researchers from Nationwide Children's Hospital describe a new paradigm for treating transcription factor-driven cancers. The study focuses on Ewing ...

Genetics

Scientists Discover Mechanism Behind 'Paused' Genes

Northwestern Medicine scientists have discovered the mechanism driving a protein that influences transcription, a crucial step in gene expression. The study, recently published in Science, could lead to drugs that control ...

Alzheimer's disease & dementia

Researchers enter race for early Alzheimer's test

According to Paul Coleman, an Alzheimer's researcher at the ASU-Banner Neurodegenerative Disease Research Center (NDRC), one of the greatest difficulties plaguing efforts to find effective treatments for Alzheimer's is the ...

Medical research

Scientists find RNA with special role in nerve healing process

Scientists may have identified a new opening to intervene in the process of healing peripheral nerve damage with the discovery that an "anti-sense" RNA (AS-RNA) is expressed when nerves are injured. Their experiments in mice ...

Ophthalmology

Scientists regenerate retinal cells in mice

Scientists have successfully regenerated cells in the retina of adult mice at the University of Washington School of Medicine in Seattle.

Neuroscience

Untangling the complex puzzle of optic nerve regeneration

The optic nerve is vital for vision—damage to this critical structure can lead to severe and irreversible loss of vision. Fengfeng Bei, PhD, a principal investigator in the Department of Neurosurgery at Brigham and Women's ...

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