Immunology

Unmasking rogue cells in the immune system

The immune system is a formidable defense against microbial intruders, identifying and eliminating threats through an extremely intricate and adaptable network of specialized cells. However, a system of such deep complexity ...

Medical research

Epigenetic program leading to vessel differentiation

Clarification of how human blood vessels are constructed is desperately needed to advance regenerative medicine. A collaborative research group from Kumamoto University, Kyoto University, and the University of Tokyo in Japan ...

Inflammatory disorders

Experimental drug targets nucleus of allergen-sensitized cells

Transcription factors, the tiny proteins that switch genes on or off in the nucleus of cells, are considered unreachable molecular targets for drugs attempting to treat medical conditions. Overcoming this challenge, researchers ...

Neuroscience

Transcriptional control of sound discrimination

Filippo Rijli and his team at the Friedrich Miescher Institute for Biomedical Research have identified two genes that control sound discrimination in the brain. The Hox2 transcription factors act in the mouse brain stem and ...

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