Diseases, Conditions, Syndromes

Scientists map the genome of a dangerous malaria vector mosquito

An international collaborative of researchers has completed work on the physical mapping of the genome of one of the malaria vectors in Central and South America—the malaria mosquito Anopheles albimanus. The map opens a ...

Medical research

Causative gene for sensorineural hearing loss identified

A causative gene for a highly common type of hearing loss (sensorineural hearing loss, or SNHL) has been identified by a group of Japanese researchers, who successfully replicated the condition using a transgenic mouse. This ...

Medical research

Elimination of senescent cells improves lung function in mice

Most cells can divide only a limited number of times and eventually undergo permanent cell cycle arrest, a state known as cellular senescence. Cellular senescence is mediated by activation of specific cellular signaling pathways ...

Genetics

Watching the luminescent gene switch

Scientists have found a way to simultaneously monitor the switching on and off of circadian "clock" genes and their effects on mouse behaviour in real-time.

Alzheimer's disease & dementia

IL-33 ameliorates Alzheimer's-like pathology and cognitive decline

Alzheimer's disease (AD) is a devastating condition with no known effective treatment. The disease is characterized by memory loss as well as impaired locomotor ability, reasoning, and judgment. Emerging evidence suggests ...

Neuroscience

The brain clock that keeps memories ticking

Just as members of an orchestra need a conductor to stay on tempo, neurons in the brain need well-timed waves of activity to organize memories across time. In the hippocampus—the brain's memory center—temporal ordering ...

Diabetes

Sticky molecules to tackle obesity and diabetes

Okayama University researchers report that the over-expression of an adhesion molecule found on the surface of fat cells appears to protect mice from developing obesity and diabetes. The findings, published in the journal ...

Genetics

What can we learn from zebrafish about human blood disorders?

Genetic regulation of the various types of blood cells in zebrafish and humans is highly similar, making it relatively easy and cost-effective to perform genetic, chemical, imaging and other molecular studies on this invaluable ...

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