Medications

New model identifies drugs that shouldn't be taken together

Any drug that is taken orally must pass through the lining of the digestive tract. Transporter proteins found on cells that line the GI tract help with this process, but for many drugs, it's not known which of those transporters ...

Oncology & Cancer

YBX1 as a key regulator of mitochondrial pyruvate uptake

Cancer metastasis is a crucial area in cancer research that directly affects patient survival and treatment outcomes. Cancer cells often undergo adaptive metabolic changes during metastasis from in situ to distant organs ...

Neuroscience

Mechanism decoded: How synapses are formed

Whether in the brain or in the muscles, wherever there are nerve cells, there are synapses. These contact points between neurons form the basis for the transmission of excitation, the communication between neurons. As in ...

Medications

How a widely used diabetes medication actually works

Physicians have used the drug metformin to treat type 2 diabetes for more than half a century, but despite its prevalence, researchers have lacked a clear understanding of how it works. Now, Yale researchers have elucidated ...

Diseases, Conditions, Syndromes

Starving the bacterium that causes pneumonia

The invitations, decorations, candles and the cake – there's a lot to remember when you organise a birthday party for a five-year-old. One thing we thankfully take for granted in Australia is that our five-year-olds reach ...

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