(HealthDay)—Models based on machine learning and optimization could improve chemotherapy regimens to be tested in phase III clinical trials without altering the toxicity outcomes, according to a study published in the May ...
May 9, 2016
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Each week in the United States, about 300 children are diagnosed with cancer. Many of them will be offered treatment as part of a clinical trial that tests different drugs or different ways to give standard drugs.
Feb 25, 2016
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Lupuzor may become the first specific and non-immunosuppressant therapy for lupus, a disabling autoimmune disease that is currently incurable. Discovered by Sylviane Muller's team in the CNRS Immunopathologie et Chimie Thérapeutique ...
Dec 15, 2015
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Adding the investigational anticancer therapeutic tivantinib to standard erlotinib treatment substantially increased progression-free survival for patients with advanced nonsquamous non–small cell lung cancer (NSCLC) who ...
Nov 9, 2015
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A new technique developed by statisticians that is helping doctors optimize the dose of a new cancer treatment patients receive in phase I/ II clinical trials was presented today by Juhee Lee, assistant professor of applied ...
Aug 10, 2015
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Treatment with the bisphosphonate zoledronate did not improve outcomes for women with chemoresistant breast cancer, according to initial results of a phase III clinical trial presented here at the 2013 San Antonio Breast ...
Dec 13, 2013
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Younger patients with colorectal cancer that has spread (metastasised) to other parts of the body represent a high-risk group that is less likely to respond to anti-cancer treatments. Their disease is more likely to progress ...
Sep 27, 2013
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University of South Florida Distinguished Professor Benjamin Djulbegovic, MD, PhD, has studied the ethics of randomized clinical trials and their effectiveness in evaluating the outcomes of new treatments for decades.
Aug 27, 2013
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Generally, FDA-approved clinical trials progress through three phases: the first shows safety, the second starts to explore effects and the third seeks to prove a drug's superiority over existing treatments. But when a drug's ...
Aug 8, 2013
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(HealthDay)—Although the U.S. Food and Drug Administration Amendments Act requires publication of the results of completed trials of cancer drugs conducted in the United States, results for almost half of the studies have ...
Jul 23, 2013
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